Two men are in custody at Kilkenny Garda Station following drug seizures at locations across the city.
The men, aged in their twenties and thirties were arrested as part of an ongoing surveillance operation.
Both men are being detained at Kilkenny Garda Station where they are being questioned by detectives.
Initially €17,500 worth of cocaine was seized and a further €23,500 worth of the drugs was seized in follow up searches in two houses in the city.
They are being detained under section 2 of the Drugs Trafficking Act.